Ketamine-Assisted Therapy

Combining medically supported ketamine with guided therapy to address the root causes of mental health conditions and create lasting change.

What is Ketamine-Assisted Therapy?

Ketamine, a commonly used anaesthetic, has also been shown to be an effective treatment for mental health conditions like depression and anxiety. At the right dose, ketamine also has psychedelic properties. It can affect perception and sensations in the body and mind, sometimes producing feelings of floating or “out-of-body” experiences, relaxation, changes to negative feelings, and dream-like states.

When combined with therapy, in the right setting, short-term changes in your state of consciousness can help you process strong emotions and memories that could otherwise be too painful or difficult to access. These personal discoveries can help to resolve some of the root causes of mental health conditions. With the guidance of a skilled therapist, you’re able to draw insights from your psychedelic experience and use these learnings to positively impact your daily life. To learn more about Ketamine-Assisted Therapy, book a free informational call with one of our health navigators.

Common Conditions Treated

  • Addiction
  • Anxiety 
  • Depression 
  • Eating Disorders
  • Obsessive Compulsive Disorder (OCD)
  • Post Traumatic Stress Disorder 
  • Chronic Pain & Chronic Illness

Ketamine is known to be particularly effective for treatment-resistant conditions

In the event of an emergency, it’s crucial to seek help as soon as possible. The Talk Suicide Helpline is available 24/7 to provide support and resources.

You can access this service by calling 1-833-456-4566 or texting 45645. 

In the case of an immediate danger to yourself or others, calling 911 should be your first course of action.

How Does It Work?

Ketamine-Assisted Therapy works on both a chemical and emotional level to facilitate lasting change. 

Ketamine treats depression in a different way than most conventional antidepressants. Ketamine targets the N-methyl-D-aspartate (NMDA) receptor, which results in increased activity of glutamate in the brain. Researchers believe this causes creation of new connections between neurons which in turn is believed to allow for new creation of positive thought and behaviour patterns in patients treated with ketamine. This is commonly referred to as neuroplasticity.

Ketamine helps to accelerate the therapeutic process. Working with a therapist during ketamine-assisted therapy makes it possible to ‘reorganize’ core experiences, see important relationships in a new light, and create a coherent and meaningful narrative that supports a long-term shift in how you feel.


What is Ketamine?

Ketamine is a synthetic medicine classified as a dissociative anesthetic. It is on the World Health Organization’s List of Essential Medicines. It was developed in 1963, approved for use in 1970, and adopted by many jurisdictions because of its rapid onset, proven safety, and short duration of action.

Though ketamine is most commonly used as an anesthetic agent in surgical and emergency department settings due to its good safety profile, it has also been used to manage acute and chronic pain conditions.

In the last two decades, ketamine has been increasingly used to address various mental health conditions, such as depression, substance use disorder, post-traumatic stress disorder, obsessive-compulsive disorder, and other mental health conditions. If you would like to learn more about how ketamine could help you in your healing journey, contact us at 1-833-NUMINUS (686-4687) or book a call.

Quels autres services liés à la kétamine offrez-vous?

Nous offrons différents types de services liés à la kétamine, dont un traitement par la kétamine, une thérapie de groupe assistée par la kétamine et SPRAVATO®. Nos traitements par la kétamine offrent de nombreuses options. Notre équipe clinique vous aidera à décider quelle forme de traitement répondra le mieux à vos besoins actuels et à vos objectifs de guérison.

 Pour déterminer le meilleur service pour vous, appelez-nous au 1 833 NUMINUS (686-4687) ou planifiez un appel.

What is the difference between Ketamine Treatment and Ketamine-Assisted Therapy?

During Ketamine Treatment or Ketamine Therapy, the focus is on the administration of medicine (ketamine) to produce a physical response. 

Ketamine-Assisted Therapy is a holistic approach to healing. During Ketamine-Assisted Therapy, ketamine is used to enhance the therapeutic process.

How is Ketamine Administered?

Ketamine can be administered by intramuscular injection (IM) or rapid dissolving tablets. We also offer SPRAVATO® nasal spray. Your team will work with you to determine which option is right for you. Each time ketamine is administered, your response will be closely monitored. 

To learn more, contact us at 1-833-NUMINUS (686-4687) or book a call.

What does the ketamine experience feel like?

The physical and emotional effects of ketamine will differ from person to person; however, common experiences include:

  • Altered states of consciousness and feeling separated from reality
  • Disruption of negative feelings
  • A dream-like or “floating” sensation
  • Relaxation of ordinary concerns and usual mindset
  • A sense of euphoria
  • A dream-like or “floating” sensation
  • An altered sense of time (losing track of time; time slowing down or speeding up)
  • Diminished or altered body sensations; some people may have an “out-of-body” experience, where awareness of the physical body is reduced
  • Tunnel vision, or seeing things through a fog
  • Pain reduction
  • Mild changes in perceptions of sounds and sights
  • It is also possible to have uncomfortable feelings as suppressed traumas arise. Safety and care are the top priorities of our team members, and your practitioners will be there to support you as you navigate any challenging experiences.

Our rooms for Ketamine Sessions have been intentionally designed to ensure your comfort and support your journey. You may choose to be in a reclined or semi-reclined position, wear eyeshades, and listen to music to enhance the experience. To learn more about our ketamine treatments, contact us at 1-833-NUMINUS (686-4687) or book a call.

Am I eligible for ketamine treatment?

To be eligible for ketamine treatment, you must be evaluated by a medical practitioner and not have any contraindications to this therapy, including any medical or other psychiatric illnesses that suggest this treatment might be unsafe. Conditions that may make you ineligible for ketamine treatment include, but are not limited to: a history of psychosis (e.g. hallucinations), mania, untreated hypertension, heart disease or stroke, and seizures. Similarly, severe liver disease, untreated thyroid disorders, or other medical conditions may require management prior to ketamine treatment.

At Numinus, ketamine treatment is only available to individuals between the ages of 14 and 65 in Quebec, Ontario, and British Columbia.

If you believe you may be eligible for ketamine treatment and would like to proceed, contact us at 1-833-NUMINUS (686-4687) or book a call.

How much does ketamine treatment cost? Will it be covered by my insurance?

Since ketamine is technically being used “off-label” to treat many mental health conditions, some insurance providers may not cover its use. SPRAVATO® is Health Canada approved for depression so may be covered through insurance. 

Contact us to help verify and explain your insurance benefits. In addition to insurance, we accept MasterCard, Visa, most health savings (HSA) cards, and cash payments. In the case we cannot accept your insurance, receipts can be provided to be submitted to your insurance company as an out-of-network provider.

For pricing information, contact us at 1-833-NUMINUS (686-4687) or book a call.

The Process

Our team will take a comprehensive approach to your care, collaborating with other health care providers to provide you with the best outcomes. Here is what you can expect from your ketamine-assisted therapy treatment.

Step 1: Connect

You’ll start by meeting our team to walk through your medical history and treatment goals. We will work with you to determine whether ketamine-assisted therapy is the right fit for you. Your safety and well-being are our primary concern.

Step 2: Prepare

The key to successful ketamine-assisted therapy is careful preparation. We’ll work together to ensure you’re set up for success. This can include exercises and guidance to help you mentally, emotionally, and physically prepare.

Step 3: Experience

Your ketamine sessions involve the administration of medicine (either via intramuscular injection, oral lozenge, or IV). These experiences may be blissful or challenging, mild or intense, depending on where you are in your healing journey. Whatever the nature of your experience, you will have the full support of our expert team, ensuring your comfort and safety. Your medical team may recommend multiple ketamine treatments for sustained results.

Step 4: Integrate

Integration is one of the most important parts of a ketamine experience, helping to maximize the healing potential. In the days following your ketamine therapy, you’ll work with your therapist to unpack your experience. If a psychedelic experience is about breaking open all that is stuck and stagnant, integration is about putting the pieces back together in a new, more balanced configuration.

Step 5: Reconnect

Healing is not linear. Sometimes we transform and sometimes we peel back an important layer, only to reveal deeper work to undertake. Reconnecting can mean pursuing additional treatment, joining one of our ongoing integration groups, or even taking what you have learned and using it to better connect with yourself and the people in your life.


Ketamine-Assisted Therapy is offered at our safe and comfortable clinics, designed with you in mind.

Montreal 393 Laurier West
393 Av. Laurier O, Montréal, QC H2V 2K3
Numinus Montreal 397 Laurier West
397 Laurier Ave W, Montreal QC H2V 2K3
Numinus Montreal Sherbrooke
5165 Sherbrooke St W, Suite 405, Montreal, QC H4A 1T6
Numinus Toronto Eglinton Avenue
491 Eglington Ave. W, Suite 100, Toronto, ON M5N 1A7
Numinus Vancouver On Commercial Drive
2555 Commercial Dr Unit 208, Vancouver, BC V5N 4C1


When delivered intravenously or as a lozenge, ketamine is used “off label” meaning that the FDA has not approved its use to treat mental health conditions. Spravato® (esketamine) is approved for treatment resistant depression.  Common side effects of ketamine include dizziness, nausea and vomiting. Ketamine raises heart rate and blood pressure, which can increase the risk of stroke or heart attack. People under the influence of ketamine may have difficulty standing up and be confused about their surroundings. Ketamine can cause vivid dreams or hallucinations, which may be intense and terrifying, and a feeling like the mind is separated from the body. Ketamine has been reported to cause apnea and respiratory depression as well as laryngospasm. Like all anesthetics, ketamine prevents users from feeling pain and, if injury occurs, a person may not know it. Frequent use of ketamine may cause bladder problems. Ketamine is also thought to increase the risk of  psychosis and seizures. Ketamine is a controlled substance because there is a risk for abuse and physical and psychological dependence. The side effects above are not the only effects you may experience. In addition, there can be various other side effects. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Refer to the medication's official prescribing information. Always consult a physician or qualified health professional on any matters regarding your mental health or on any opinions expressed within this article.

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